Xcrossflow^® Hollow-Fiber Membrane Modules

XAccurflow^®High-Precision Diaphragm Pump

Exospure^® Tubing & Components

ArcXpure^® Tubing Manifolds

Exodc^® Fluid Components

Xezconnector^®Quick Connectors

· Xcrossflow^® open hollow-fiber channels with asymmetric membrane fiber cross-sections → High flux, high retention, low shear, and fouling resistance — for stable, repeatable filtration

Pressure capability up to 6 bar→Meets clarification filtration requirements with improved filtration efficiency

· Single-use tubing and Xezconnector^® quick connectors for rapid line setup → Shorter batch changeover time and lower cross-contamination risk

During concentration and buffer exchange (UF/DF), high-fold concentration and thorough buffer exchange must be achieved while controlling transmembrane pressure (TMP) and flow rate. Pump flow stability, low shear, and system controllability directly affect yield, membrane lifetime, and process scalability.

XAccurflow^® High-Precision Diaphragm Pump

Exods^®Manual Cassette Ultrafiltration System

（Lab）

Exods^®Manual Hollow-Fiber Ultrafiltration System

（Lab）

Exods^® Fully Automatic Intelligent Ultrafiltration System

（Pilot / Production）

Exods^®Fully Automatic Ultrafiltration System（GMP）

Exodc^® Fluid Components

Xezconnector^®Quick Connectors

· XAccurflow^® high-precision diaphragm pump — high flow accuracy, comparable to mass flow meters (±0.5%–1%)→Precise, stable tangential flow rate — reduces the risk of concentration polarization；

Low shear, continuous stable transfer→Prevents flow decay at elevated pressures, protecting cassettes and fluid activity

Proportional linear output across the full backpressure range, with stable flow output at 6 bar → Stable TMP control — consistent membrane flux and excellent batch-to-batch consistency

· Exods^® manual & automatic ultrafiltration systems — integrated manifold, forged diaphragm valves, and dead-leg-free tubing design→ Controllable bioburden with verifiable CIP effectiveness

Automatic systems support coordinated multi-parameter control of TMP/flow rate/pressure→ Eliminates manual operation errors — automatic concentration, constant-volume/batch automatic buffer exchange, and automatic product collection

Meets scale-up needs across R&D, pilot, and full-scale production

· Single-use tubing and Xezconnector^® quick connectors for rapid line setup →Shorter batch changeover time and lower cross-contamination risk

In chromatography, loading volume and gradient elution precision directly determine resolution, purity, and yield; chromatography systems demand high flow accuracy, low pulsation, and pressure capability from pumps.

XAccurflow^® High-Precision Diaphragm Pump

Exospure^®EPS  Transfer Tubing

Exodc^® Fluid Components

Xezconnector^® Quick Connectors

·High flow accuracy, comparable to mass flow meters (±0.5%–1%)→ Accurate loading volume and controllable gradient elution concentration — improved purity and yield of the target product;

 Supports extremely low speeds down to 1 rpm with pump speed linearity R² > 0.99 → Maintains linear output during long, low-flow-rate elution — stable elution peak shape;

Low-shear four-diaphragm alternating motion for ultra-low pulsation output → Reduces pulsation disturbance to the column bed, extending chromatography resin lifetime;

Pressure capability up to 6 bar→Meets chromatography process requirements with improved chromatography efficiency

· Single-use tubing and Xezconnector^® quick connectors for rapid line setup → Shorter batch changeover time and lower cross-contamination risk

During concentration and buffer exchange (UF/DF), high-fold concentration and thorough buffer exchange must be achieved while controlling transmembrane pressure (TMP) and flow rate. Pump flow stability, low shear, and system controllability directly affect yield, membrane lifetime, and process scalability.

XAccurflow^® High-Precision Diaphragm Pump

Exods^®Manual Cassette Ultrafiltration System

（Lab）

Exods^®Manual Hollow-Fiber Ultrafiltration System

（Lab）

Exods^® Fully Automatic Intelligent Ultrafiltration System

（Pilot / Production）

Exods^®Fully Automatic Ultrafiltration System（GMP）

Exodc^® Fluid Components

Xezconnector^®Quick Connectors

· XAccurflow^® high-precision diaphragm pump — high flow accuracy, comparable to mass flow meters (±0.5%–1%)→Precise, stable tangential flow rate — reduces the risk of concentration polarization；

Low shear, continuous stable transfer→Prevents flow decay at elevated pressures, protecting cassettes and fluid activity

Proportional linear output across the full backpressure range, with stable flow output at 6 bar → Stable TMP control — consistent membrane flux and excellent batch-to-batch consistency

· Exods^® manual & automatic ultrafiltration systems — integrated manifold, forged diaphragm valves, and dead-leg-free tubing design→ Controllable bioburden with verifiable CIP effectiveness

Automatic systems support coordinated multi-parameter control of TMP/flow rate/pressure→ Eliminates manual operation errors — automatic concentration, constant-volume/batch automatic buffer exchange, and automatic product collection

Meets scale-up needs across R&D, pilot, and full-scale production

· Single-use tubing and Xezconnector^® quick connectors for rapid line setup →Shorter batch changeover time and lower cross-contamination risk

0.2 μm sterile filtration provides a microbial barrier for drug substance/intermediates. Filter feed must be delivered at a stable, low differential pressure to prevent pressure fluctuations from affecting membrane lifetime and filter integrity.

XAccurflow^®High-Precision Diaphragm Pump

Exospure^®Tubing & Components

Exodc^®Fluid Components

Xezconnector^®Quick Connectorstors

→ Reduces target antibody aggregation and activity loss

Pressure capability up to 6 bar→Meets sterile filtration process requirements with improved filtration efficiency

· Single-use tubing and Xezconnector^® quick connectors for rapid line setup → Shorter batch changeover time and lower cross-contamination risk

Drug product filling requires precise metering, aseptic transfer, and durable, wear-resistant pump tubing, avoiding the introduction of particles, microorganisms, and metal ions during filling—while meeting the demands of high batch yield and rapid changeover.

Xpanflow^® Peristaltic Pump

Xdspure^®Tubing Modules、

Exospure^® EPT Abrasion-Resistant Tubing

Exospure^® EPS Transfer Tubing

·

Xpanflow^® peristaltic pump maintains high flow rates and precise constant flow at low speeds→ Accurate filling metering with stable fill rates, adaptable to different fill volumes

Peristaltic pump tubing delivers contact-based transfer → with no metal parts contacting the fluid

Xdspure^® tubing Modules (continuous operation >1,000 h) fit quickly and precisely into the pump head → Less downtime for tube changes — higher throughput

Exospure^® EPT wear-resistant tubing (TPV, wear-resistant, low particle shedding)→ Minimal particle generation during long-term operation — safeguards drug product cleanliness

Exospure^® EPS transfer tubing → Stable pressurized transfer of the sterile-filtered drug solution to the filling point — lower leakage risk