Xcrossflow^® Hollow-Fiber Membrane Modules

Name: Xcrossflow ® Hollow-Fiber Membrane Modules
Brand: Xcrossflow

Broad Pore-Size Range · Split-Body Design

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Introduction Features Applications Parameters Other Contact Us

Introduction

Our Xcrossflow^{^®} Hollow-Fiber Membrane Modules are designed for microfiltration and ultrafiltration applications, with multiple sizes available to support effortless process scale-up. An open hollow-fiber flow path paired with an asymmetric membrane cross-section delivers high flux, high retention, low shear, and fouling resistance for stable, repeatable filtration — protecting the activity and integrity of antibodies, viral vectors, and other large biomolecules throughout the process.

Features

High flux and low shear with asymmetric fiber cross-section for gentle handling of sensitive biomolecules.
316L stainless steel housing with replaceable cartridges and split-body design for lower cost of ownership.
Wide MWCO and pore-size range from 5 kDa to 0.2 μm covering a full matrix of separation resolutions.
Linear scale-up across Series X2 / X5 / X6 / X9 with membrane areas up to 9.8 m² for a seamless move to full-scale production

Application Scenarios

Cell concentration and lysate clarification
Viral concentration and purification
Recombinant protein and vaccine purification
Diafiltration of nano/latex particles

Technical Specifications

Item	Description
Materials	Membrane fibers: mPES, compliant with USP87, USP88, USP661
	Inner housing: PSU, compliant with ISO10993-5, ISO10993-6, ISO10993-10, ISO10993-11
	Sealant: epoxy resin, compliant with USP87, USP88
	Seals and gaskets: silicone, compliant with USP87, USP88, 21CFR 177.2600
	Housing: 316L
MWCO	5KD, 8KD, 10KD, 30KD, 50KD, 100KD, 300KD, 750KD, 0.1um, 0.2um
Fiber Inner Diameter	1mm, 0.5mm
Inner Housing Diameter	20mm, 40mm, 55mm, 90mm
Inner Housing Length	260mm, 510mm, 940mm
Design Feature	Split design

Other

Ordering Information

MWCO	Fiber ID	Series X2
MWCO	Fiber ID	Flow Channel Length	Membrane Area	Flow Channel Length	Membrane Area
	mm	mm	m²	mm	m²
5KD	0.5	210	0.050	460	0.115
5KD	1	210	0.039	460	0.086
8KD	0.5	210	0.050	460	0.115
8KD	1	210	0.039	460	0.086
10KD	0.5	210	0.050	460	0.115
10KD	1	210	0.039	460	0.086
30KD	0.5	210	0.050	460	0.115
30KD	1	210	0.039	460	0.086
50KD	0.5	210	0.050	460	0.115
50KD	1	210	0.039	460	0.086
100KD	0.5	210	0.050	460	0.115
100KD	1	210	0.039	460	0.086
300KD	0.5	210	0.050	460	0.115
300KD	1	210	0.039	460	0.086
750KD	0.5	210	0.050	460	0.115
750KD	1	210	0.039	460	0.086
0.1um	0.5	210	0.050	460	0.115
0.1um	1	210	0.039	460	0.086
0.2um	0.5	210	0.050	460	0.115
0.2um	1	210	0.039	460	0.086

MWCO	Fiber ID	Series X5
MWCO	Fiber ID	Flow Channel Length	Membrane Area	Flow Channel Length	Membrane Area
	mm	mm	m²	mm	m²
5KD	0.5	210	0.390	460	0.860
5KD	1	210	0.316	460	0.690
8KD	0.5	210	0.390	460	0.860
8KD	1	210	0.316	460	0.690
10KD	0.5	210	0.390	460	0.860
10KD	1	210	0.316	460	0.690
30KD	0.5	210	0.390	460	0.860
30KD	1	210	0.316	460	0.690
50KD	0.5	210	0.390	460	0.860
50KD	1	210	0.316	460	0.690
100KD	0.5	210	0.390	460	0.860
100KD	1	210	0.316	460	0.690
300KD	0.5	210	0.390	460	0.860
300KD	1	210	0.316	460	0.690
750KD	0.5	210	0.390	460	0.860
750KD	1	210	0.316	460	0.690
0.1um	0.5	210	0.390	460	0.860
0.1um	1	210	0.316	460	0.690
0.2um	0.5	210	0.390	460	0.860
0.2um	1	210	0.316	460	0.690

MWCO	Fiber ID	Series X6
MWCO	Fiber ID	Flow Channel Length	Membrane Area	Flow Channel Length	Membrane Area	Flow Channel Length	Membrane Area
	mm	mm	m²	mm	m²	mm	m²
5KD	0.5	210	0.82	460	1.80	880	3.39
5KD	1	210	0.60	460	1.30	880	2.50
8KD	0.5	210	0.82	460	1.80	880	3.39
8KD	1	210	0.60	460	1.30	880	2.50
10KD	0.5	210	0.82	460	1.80	880	3.39
10KD	1	210	0.60	460	1.30	880	2.50
30KD	0.5	210	0.82	460	1.80	880	3.39
30KD	1	210	0.60	460	1.30	880	2.50
50KD	0.5	210	0.82	460	1.80	880	3.39
50KD	1	210	0.60	460	1.30	880	2.50
100KD	0.5	210	0.82	460	1.80	880	3.39
100KD	1	210	0.60	460	1.30	880	2.50
300KD	0.5	210	0.82	460	1.80	880	3.39
300KD	1	210	0.60	460	1.30	880	2.50
750KD	0.5	210	0.82	460	1.80	880	3.39
750KD	1	210	0.60	460	1.30	880	2.50
0.1um	0.5	210	0.82	460	1.80	880	3.39
0.1um	1	210	0.60	460	1.30	880	2.50
0.2um	0.5	210	0.82	460	1.80	880	3.39
0.2um	1	210	0.60	460	1.30	880	2.50

MWCO	Fiber ID	Series X9
MWCO	Fiber ID	Flow Channel Length	Membrane Area	Flow Channel Length	Membrane Area
	mm	mm	m²	mm	m²
5KD	0.5	460	5.08	880	9.80
5KD	1	460	3.30	880	6.39
8KD	0.5	460	5.08	880	9.80
8KD	1	460	3.30	880	6.39
10KD	0.5	460	5.08	880	9.80
10KD	1	460	3.30	880	6.39
30KD	0.5	460	5.08	880	9.80
30KD	1	460	3.30	880	6.39
50KD	0.5	460	5.08	880	9.80
50KD	1	460	3.30	880	6.39
100KD	0.5	460	5.08	880	9.80
100KD	1	460	3.30	880	6.39
300KD	0.5	460	5.08	880	9.80
300KD	1	460	3.30	880	6.39
750KD	0.5	460	5.08	880	9.80
750KD	1	460	3.30	880	6.39
0.1um	0.5	460	5.08	880	9.80
0.1um	1	460	3.30	880	6.39
0.2um	0.5	460	5.08	880	9.80
0.2um	1	460	3.30	880	6.39